As many of you may or may not know I’m currently battling Stage IV High Risk Neuroblastoma Cancer. Neuroblastoma is primarily found in children and is extremely rare for adults to get.
Cancer starts when cells in the body begin to grow out of control and crowd out normal cells. Cells in nearly any part of the body can become cancer, and can spread to other areas of the body.
The types of cancers that develop in children are often different from the types that develop in adults.
Neuroblastoma starts in certain very early forms of nerve cells, most often found in an embryo or fetus. (The term neurorefers to nerves, while blastoma refers to a cancer that affects immature or developing cells). This type of cancer occurs most often in infants and young children. It is rare in children older than 10 years and adults.
To understand neuroblastoma, it helps to know about the sympathetic nervous system, which is where these tumors start.
The sympathetic nervous system
The brain, spinal cord, and the nerves that reach out from them to all areas of the body are all part of the nervous system. The nervous system is needed for thinking, sensation, and movement, among other things.
Part of the nervous system also controls body functions we are rarely aware of, such as heart rate, breathing, blood pressure, digestion, and other functions. This part of the nervous system is known as the autonomic nervous system.
The sympathetic nervous system is part of the autonomic nervous system. It includes:
- Nerve fibers that run along either side the spinal cord.
- Clusters of nerve cells called ganglia (plural of ganglion) at certain points along the path of the nerve fibers.
- Nerve-like cells found in the medulla (center) of the adrenal glands. The adrenals are small glands that sit on top of each kidney. These glands make hormones (such as adrenaline [epinephrine]) that help control heart rate, blood pressure, blood sugar, and how the body reacts to stress.
The main cells that make up the nervous system are called nerve cells or neurons. These cells interact with other types of cells in the body by releasing tiny amounts of chemicals (hormones). This is important, because neuroblastoma cells often release certain chemicals that can cause symptoms.
Neuroblastomas are cancers that start in early nerve cells (called neuroblasts) of the sympathetic nervous system, so they can be found anywhere along this system.
- Most neuroblastomas begin in sympathetic nerve ganglia in the abdomen, about half of these start in the adrenal gland.
- Most of the rest start in sympathetic ganglia near the spine in the chest or neck, or in the pelvis. Mine was in my left pelvis area!
Some neuroblastomas grow and spread quickly, while others grow slowly. Sometimes, in very young children, the cancer cells die for no reason and the tumor goes away on its own. In other cases, the cells sometimes mature on their own into normal ganglion cells and stop dividing (this makes the tumor a benign ganglioneuroma).
I hope this was helpful in understanding what kind of cancer I have! Cheers!